Libro

Descripción

The Present study aims to characterize the chemical profile of phenolic compounds and some biological activities of Astragalus gombiformis Pomel of Fabaceae family The phytochemical study of A. gombiformis extracts by LC-ESI-MS revealed the presence of 17 phenolic compounds of which Cirsiliol or Diméthoxyflavone (DMF) was detected as the main compounds in this plant. The Antioxidant activity was evaluated through chemical tests: DPPH, ABTS, CUPRAC, GOR and β-carotene. The results obtained showed that:  The butanolic fraction of the flowers showed the best antiradical activity with the DPPH and ABTS tests.  The flowers and whole plant extracts showed the best activity with the CUPRAC test.  The whole plant extract showed the best activity with the β-carotene test and Low activity with GOR. All A. gombiformis extracts are completely ineffective as tyrosine’s inhibitors. However, the whole plant extract is the most effective against the urease enzyme. The antidiabetic activity was evaluated by the inhibition method of α-amylase and α-glucosidase.